Phytochemical Analysis and Antimalarial Activity of Usnea sp. from South Sulawesi against Plasmodium falciparum
نویسندگان
چکیده
منابع مشابه
Assessment of antimalarial activity against Plasmodium falciparum and phytochemical screening of some Yemeni medicinal plants
Developing countries, where malaria is one of the most prevalent diseases, still rely on traditional medicine as a source for the treatment of this disease. In the present study, six selected plants (Acalypha fruticosa, Azadirachta indica, Cissus rotundifolia, Echium rauwalfii, Dendrosicyos socotrana and Boswellia elongata) commonly used in Yemen by traditional healers for the treatment of mala...
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The in vitro activity of rac-mefloquine hydrochloride and its pure enantiomers was tested against a chloroquine-resistant (PF.IBS2) strain of Plasmodium falciparum. The parasite isolated from Iranian patients was cultured in vitro by the candle jar method described by Tranger and Jensen and was exposed to the racemic mefloquine or its enantiomers over the concentration range of 10-9 to 10-4 M. ...
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OZ277 is a newly developed, fully synthetic endoperoxide antimalarial that we tested against field isolates from Gabon. A comparison of activities of OZ277 with artesunate, mefloquine, and chloroquine showed OZ277 to be highly active against all parasite isolates. Artesunate and mefloquine also showed potent antiparasitic activity, but all isolates were chloroquine resistant.
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Received 10th December, 2012 Received in revised form 20th, December, 2012 Accepted 5th January, 2013 Published online 31 January, 2013 Objective: The antiplasmodial activity of pure n e e m l i m o n o i d s (azadirachtin, salannin, deacetylgedunin, gedunin, 17-h ydroxyazadiradione and deacetylnimbin) was evaluated in vitro against the chloroquine resistant and-sensitive strains of P. falcipar...
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In vivo and in vitro assessments of the response of P. falciparum to chloroquine using WHO standard kits and techniques were carried out in I ran Shahr, Sistan and Baluchestan province of Iran in 1985. In the in vivo assessment, 24 malaria patients treated with chloroquine (25mg/kg over three days) were followed up for one to four weeks. The mean parasite clearance time was 4.3 days and in...
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ژورنال
عنوان ژورنال: International Journal of Current Microbiology and Applied Sciences
سال: 2017
ISSN: 2319-7692,2319-7706
DOI: 10.20546/ijcmas.2017.609.203